Selective packaging of the influenza A genome and consequences for genetic reassortment.

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GERBER, Marie, ISEL, C., MOULES, V. et MARQUET, Roland, 2014. Selective packaging of the influenza A genome and consequences for genetic reassortment. Trends in Microbiology [en ligne]. 2014. Vol. 22, n° 8pp. 446-455. [Consultésans date]. DOI 10.1016/j.tim.2014.04.001. Consulté de : http://www.ncbi.nlm.nih.gov/pubmed/24798745?dopt=Abstract
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Auteurs Marie Gerber
C Isel
V Moules
Roland Marquet
Unité de recherche du site IBMC - Architecture et Réactivité de l'ARN - ARN - UPR9002
Langue

en
Volume

22
Numéro

8
Page de début

446
Page de fin

455
Date de première publication

2014
ISSN

1878-4380
Titre de la source (revue, livre…)

Trends in Microbiology
Résumé

Influenza A viruses package their segmented RNA genome in a selective manner. Electron tomography, biochemical assays, and replication assays of viruses produced by reverse genetics recently unveiled molecular details of this mechanism, whereby Show moreInfluenza A viruses package their segmented RNA genome in a selective manner. Electron tomography, biochemical assays, and replication assays of viruses produced by reverse genetics recently unveiled molecular details of this mechanism, whereby different influenza viral strains form different and unique networks of direct intermolecular RNA-RNA interactions. Together with detailed views of the three-dimensional structure of the viral ribonucleoparticles, these recent advances help us understand the rules that govern genome packaging. They also have deep implications for the genetic reassortment processes, which are responsible for devastating pandemics. Show less
DOI 10.1016/j.tim.2014.04.001
Éditeur

Elsevier (Cell Press)
URL éditeur http://www.ncbi.nlm.nih.gov/pubmed/24798745?dopt=Abstract
Type de publication

journal article
Type de publication

ACL
Fonction

aut
ctb
URL https://univoak.eu/islandora/object/islandora:54776