Impact of Setting up an "Endocarditis Team" on the Management of Infective Endocarditis
| Pas de texte intégral | |
|---|---|
| Auteurs |
Yvon Ruch Jean-philippe Mazzucotelli François Lefebvre Aurélie Martin Nicolas Lefebvre Nawal Douiri Philippe Riegel Tam Hoang Minh Hélène Petit-Eisenmann Yves Hansmann Xavier Argemi |
| Unité de recherche du site |
Nanomédecine Régénérative - NanoRegMed - UMRS1260 Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe - VBP - EA7290 Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe - VBP - UR7290 |
| Langue |
en |
| Volume |
6 |
| Numéro |
9 |
| Date de première publication |
2019 |
| ISSN |
2328-8957 |
| Titre de la source (revue, livre…) |
Open Forum Infectious Diseases |
| Résumé |
Background: Infective endocarditis (IE) remains a severe disease with a high mortality rate. Therefore, guidelines encourage the setup of a multidisciplinary group in reference centers. The present study evaluated the impact of this "Endocarditis Show moreBackground: Infective endocarditis (IE) remains a severe disease with a high mortality rate. Therefore, guidelines encourage the setup of a multidisciplinary group in reference centers. The present study evaluated the impact of this "Endocarditis Team" (ET). Methods: We conducted a monocentric observational study at Strasbourg University Hospital, Strasbourg, France, between 2012 and 2017. The primary end point was in-hospital mortality. Secondary end points were 6-month and 1-year mortality, surgery rate, time to surgical procedure, duration of effective antibiotic therapy, length of in-hospital stay, and sequelae. We also assessed predictors of in-hospital mortality. Results: We analyzed 391 episodes of IE. In the post-ET period, there was a nonsignificant decrease in in-hospital mortality (20.3% vs 14.7%, respectively; P = .27) and sequelae, along with a significant reduction in time to surgery (16.4 vs 10.3 days, respectively; P = .049), duration of antibiotic therapy (55.2 vs 47.2 days, respectively; P < .001), and length of in-hospital stay (40.6 vs 31.9 days, respectively; P < .01). In a multivariate analysis, the post-ET period was positively associated with survival (odds ratio, 0.45; 95% confidence interval, 0.20-0.96; P = .048). Conclusions: This multidisciplinary approach exerted a positive impact on the management of IE and should be considered in all hospitals managing IE. Show less |
| DOI | 10.1093/ofid/ofz308 |
| Type de publication |
journal article |
| Type de publication |
ACL |
| Domaine |
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie |
| Mots-clés |
cardiac surgery |
| Unité de recherche extérieure au site |
Department of Infectious Disease, Strasbourg University Hospital, Strasbourg, France |
| Fonction |
aut |
| Identifiant idREF |
069254443 124443079 172264804 07402311X 156982870 |
| Audience |
Non spécifiée |
| Envoyer vers HAL |
5 |
| URL | https://univoak.eu/islandora/object/islandora:90190 |