The adaptor hypothesis revisited.

Citer cette référence
IBBA, M., BECKER, Hubert, STATHOPOULOS, C., TUMBULA, D L et SÖLL, D., 2000. The adaptor hypothesis revisited. Trends in biochemical sciences. juillet 2000. Vol. 25, n° 7pp. 311-6. DOI 10.1016/s0968-0004(00)01600-5. 1. journal article. 2. research support, non-u.s. gov't. 3. review. 4. 2000 Jul. 5. . 6. imported.
Pas de texte intégral
Auteurs M Ibba
Hubert Becker
C Stathopoulos
D L Tumbula
D Söll
Langue

en
Volume

25
Numéro

7
Date de première publication

2000-07
Titre de la source (revue, livre…)

Trends in biochemical sciences
Résumé

As originally postulated in Crick's Adaptor hypothesis, the faithful synthesis of proteins from messenger RNA is dependent on the presence of perfectly acylated tRNAs. The hypothesis also suggested that each aminoacyl-tRNA would be made by a unique Show moreAs originally postulated in Crick's Adaptor hypothesis, the faithful synthesis of proteins from messenger RNA is dependent on the presence of perfectly acylated tRNAs. The hypothesis also suggested that each aminoacyl-tRNA would be made by a unique enzyme. Recent data have now forced a revision of this latter point, with an increasingly diverse array of enzymes and pathways being implicated in aminoacyl-tRNA synthesis. These unexpected findings have far-reaching implications for our understanding of protein synthesis and its origins. Show less
DOI 10.1016/s0968-0004(00)01600-5
Titre abrégé de la source

Trends Biochem Sci
Type de publication

journal article
Type de publication

ACL
Topic

Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire
genetics
metabolism
classification
biosynthesis
PMID 10871880
Unité de recherche extérieure au site

Center for Biomolecular Recognition, Dept of Medical Biochemistry and Genetics, Laboratory B, The Panum Institute, Blegdamsvej 3c, DK-2200, Copenhagen N, Denmark
Audience

Non spécifiée
Envoyer vers HAL

5
URL https://univoak.eu/islandora/object/islandora:98482