Chimie de la matière complexe - CMC - UMR7140

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Analysis of monoclonal antibody by a novel CE-UV/MALDI-MS interface
BIACCHI, Michael, BHAJUN, Ricky, SAÏD, Nassur, BECK, Alain, FRANCOIS, Yannis Nicolas et LEIZE-WAGNER, Emmanuelle, sans date. Analysis of monoclonal antibody by a novel CE-UV/MALDI-MS interface: CE and CEC. ELECTROPHORESIS. sans date. Vol. 35, n° 20pp. 2986-2995. DOI 10.1002/elps.201400276. 1. .
Characterization of cetuximab Fc/2 dimers by off-line CZE-MS
FRANÇOIS, Yannis-Nicolas, BIACCHI, Michael, SAID, Nassur, RENARD, Charly, BECK, Alain, GAHOUAL, Rabah et LEIZE-WAGNER, Emmanuelle, sans date. Characterization of cetuximab Fc/2 dimers by off-line CZE-MS. Analytica Chimica Acta. sans date. Vol. 908, pp. 168-176. DOI 10.1016/j.aca.2015.12.033. 1. .
Chemical cross-linking and mass spectrometry to determine the subunit interaction network in a recombinant human SAGA HAT subcomplex
NGUYEN HUYNH, Nha Thi T., SHAROV, Grigory, POTEL, Clément, FICHTER, Pelagie, TROWITZSCH, S., BERGER, I., LAMOUR, Valerie, SCHULTZ, Patrick, POTIER-HOLLER, Noelle et LEIZE-WAGNER, Emmanuelle, 2015. Chemical cross-linking and mass spectrometry to determine the subunit interaction network in a recombinant human SAGA HAT subcomplex. Protein Science [en ligne]. 14 avril 2015. Vol. 24, n° 8pp. 1232-1246. [Consultésans date]. DOI 10.1002/pro.2676. Consulté de : https://onlinelibrary.wiley.com/doi/abs/10.1002/pro.26761. .
Cutting-edge capillary electrophoresis characterization of monoclonal antibodies and related products
GAHOUAL, Rabah, BECK, Alain, LEIZE-WAGNER, Emmanuelle et FRANÇOIS, Yannis-Nicolas, sans date. Cutting-edge capillary electrophoresis characterization of monoclonal antibodies and related products. Journal of Chromatography B. sans date. Vol. 1032, pp. 61-78. DOI 10.1016/j.jchromb.2016.05.028. 1. .
Extraordinary stability of hemocyanins from L. polyphemus and E. californicum studied using infrared spectroscopy from 294 to 20 K
KHALIL, Mireille, BOUBEGTITEN-FEZOUA, Zahia, HELLMANN, Nadja et HELLWIG, Petra, sans date. Extraordinary stability of hemocyanins from L. polyphemus and E. californicum studied using infrared spectroscopy from 294 to 20 K. Phys. Chem. Chem. Phys. [en ligne]. sans date. Vol. 18, n° 41pp. 28732-28739. [Consultésans date]. DOI 10.1039/C6CP03510H. Consulté de : http://pubs.rsc.org/en/Content/ArticleLanding/2016/CP/C6CP03510H#!divAbstract1. .
Full Antibody Primary Structure and Microvariant Characterization in a Single Injection Using Transient Isotachophoresis and Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry
GAHOUAL, Rabah, BUSNEL, Jean-Marc, BECK, Alain, FRANÇOIS, Yannis-Nicolas et LEIZE-WAGNER, Emmanuelle, sans date. Full Antibody Primary Structure and Microvariant Characterization in a Single Injection Using Transient Isotachophoresis and Sheathless Capillary Electrophoresis–Tandem Mass Spectrometry. Analytical Chemistry. sans date. Vol. 86, n° 18pp. 9074-9081. DOI 10.1021/ac502378e. 1. .
Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-Line Capillary Zone Electrophoresis-UV/Electrospray Ionization-MS
BIACCHI, Michael, GAHOUAL, Rabah, SAID, Nassur, BECK, Alain, LEIZE-WAGNER, Emmanuelle et FRANCOIS, Yannis, sans date. Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-Line Capillary Zone Electrophoresis-UV/Electrospray Ionization-MS. Analytical Chemistry. sans date. Vol. 87, n° 12pp. 6240-6250. DOI 10.1021/acs.analchem.5b00928. 1. .
High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method
GOYON, Alexandre, FRANCOIS, Yannis Nicolas, COLAS, Olivier, BECK, Alain, VEUTHEY, Jean Luc et GUILLARME, Davy, 2018. High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method. ELECTROPHORESIS. 4 juin 2018. Vol. 39, n° 16pp. 2083-2090. DOI 10.1002/elps.201800131.
Identification of Zr(IV)-based architectures generated from ligands incorporating the 2,2′-biphenolato unit
MIAO, Chengrui, KHALIL, Georges, CHAUMONT, Alain, MOBIAN, Pierre et HENRY, Marc, sans date. Identification of Zr(IV)-based architectures generated from ligands incorporating the 2,2′-biphenolato unit. Dalton Trans. [en ligne]. sans date. Vol. 45, n° 19pp. 7998-8007. [Consultésans date]. DOI 10.1039/C6DT00471G. Consulté de : http://pubs.rsc.org/en/Content/ArticleHtml/2016/DT/c6dt00471g1. .
Iminosugar‐Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels
LEPAGE, Mathieu, SCHNEIDER, Jérémy, BODLENNER, Anne, DE RICCARDIS, Francesco, SCHMITT, Marjorie, TARNUS, Celine, NGUYEN HUYNH, Nha Thi, FRANCOIS, Yannis-Nicolas, LEIZE-WAGNER, Emmanuelle, BIRCK, Catherine, COUSIDO-SIAH, Alexandra, PODJARNY, Alberto, IZZO, Irene, COMPAIN, Philippe et MELI, Alessandra, 2016. Iminosugar‐Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels. Chemistry - A European Journal [en ligne]. 4 avril 2016. [Consultésans date]. DOI 10.1002/chem.201600338. Consulté de : http://onlinelibrary.wiley.com/doi/10.1002/chem.201600338/abstract1. .
Improvement of Mitochondria Extract from Saccharomyces cerevisiae Characterization in Shotgun Proteomics Using Sheathless Capillary Electrophoresis Coupled to Tandem Mass Spectrometry
IBRAHIM, Marianne, GAHOUAL, Rabah, ENKLER, Ludovic, BECKER, Hubert D., CHICHER, Johana, HAMMAN, Philippe, FRANÇOIS, Yannis N., KUHN, Lauriane et LEIZE-WAGNER, Emmanuelle, 2016. Improvement of Mitochondria Extract from Saccharomyces cerevisiae Characterization in Shotgun Proteomics Using Sheathless Capillary Electrophoresis Coupled to Tandem Mass Spectrometry. Journal of Chromatographic Science [en ligne]. 2016. Vol. 54, n° 4pp. 653-663. [Consultésans date]. DOI 10.1093/chromsci/bmw005. Consulté de : http://www.ncbi.nlm.nih.gov/pubmed/268603951. 2016 Feb 8.
Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS
GAHOUAL, Rabah, BECK, Alain, FRANÇOIS, Yannis-Nicolas et LEIZE-WAGNER, Emmanuelle, sans date. Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS: Characterization of Asn and Asp PTMs by CZE-ESI-MS. Journal of Mass Spectrometry. sans date. Vol. 51, n° 2pp. 150-158. DOI 10.1002/jms.3735. 1. .
Intact monoclonal antibodies separation and analysis by sheathless capillary electrophoresis-mass spectrometry
GIORGETTI, Jeremie, LECHNER, Antony, DEL NERO, Elise, BECK, Alain, FRANÇOIS, Yannis-Nicolas et LEIZE-WAGNER, Emmanuelle, sans date. Intact monoclonal antibodies separation and analysis by sheathless capillary electrophoresis-mass spectrometry. European Journal of Mass Spectrometry. sans date. pp. 146906671880779. DOI 10.1177/1469066718807798. 1. .
Mapping of the Available Chemical Space versus the Chemical Universe of Lead-Like Compounds
LIN, Arkadii, HORVATH, Dragos, AFONINA, Valentina, MARCOU, Gilles, REYMOND, Jean-Louis et VARNEK, Alexandre, sans date. Mapping of the Available Chemical Space versus the Chemical Universe of Lead-Like Compounds. ChemMedChem. sans date. Vol. 13, n° 6pp. 540-554. DOI 10.1002/cmdc.201700561. 1. .
Mimicking the Chemistry of Natural Eumelanin Synthesis: The KE Sequence in Polypeptides and in Proteins Allows for a Specific Control of Nanosized Functional Polydopamine Formation
BERGTOLD, Camille, HAUSER, Daniel, CHAUMONT, Alain, EL YAKHLIFI, Salima, MATEESCU, Mihaela, MEYER, Florent, METZ-BOUTIGUE, Marie Hélène, FRISCH, Benoît, SCHAAF, Pierre, IHIAWAKRIM, Dris, ERSEN, Ovidiu, MONNIER, Christophe A., PETRI-FINK, Alke, ROTHEN-RUTISHAUSER, Barbara et BALL, Vincent, sans date. Mimicking the Chemistry of Natural Eumelanin Synthesis: The KE Sequence in Polypeptides and in Proteins Allows for a Specific Control of Nanosized Functional Polydopamine Formation. Biomacromolecules. sans date. Vol. 19, n° 9pp. 3693-3704. DOI 10.1021/acs.biomac.8b00818. 1. .
Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry
GAHOUAL, Rabah, BIACCHI, Michaël, CHICHER, Johana, KUHN, Lauriane, HAMMANN, Philippe, BECK, Alain, LEIZE-WAGNER, Emmanuelle et FRANCOIS, Yannis N, sans date. Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry. mAbs. sans date. Vol. 6, n° 6pp. 1464-1473. DOI 10.4161/mabs.36305. 1. .
Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation
GIORGETTI, Jeremie, D’ATRI, Valentina, CANONGE, Julie, LECHNER, Antony, GUILLARME, Davy, COLAS, Olivier, WAGNER-ROUSSET, Elsa, BECK, Alain, LEIZE-WAGNER, Emmanuelle et FRANÇOIS, Yannis-Nicolas, sans date. Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation. Talanta. sans date. Vol. 178, pp. 530-537. DOI 10.1016/j.talanta.2017.09.083. 1. .
Monomeric Ti(IV)-based complexes incorporating luminescent nitrogen ligands: synthesis, structural characterization, emission spectroscopy and cytotoxic activities
KHALIL, Georges, ORVAIN, Christophe, FANG, Lu, BARLOY, Laurent, CHAUMONT, Alain, GAIDDON, Christian, HENRY, Marc, KYRITSAKAS, Nathalie et MOBIAN, Pierre, sans date. Monomeric Ti(IV)-based complexes incorporating luminescent nitrogen ligands: synthesis, structural characterization, emission spectroscopy and cytotoxic activities. Dalton Trans. [en ligne]. sans date. Vol. 45, n° 47pp. 19072-19085. [Consultésans date]. DOI 10.1039/C6DT03477B. Consulté de : http://pubs.rsc.org/en/content/articlehtml/2016/dt/c6dt03477b1. .
Multi-task generative topographic mapping in virtual screening
LIN, Arkadii, HORVATH, Dragos, MARCOU, Gilles, BECK, Bernd et VARNEK, Alexandre, 2019. Multi-task generative topographic mapping in virtual screening. Journal of Computer-Aided Molecular Design. 9 février 2019. Vol. 33, n° 3pp. 331-343. DOI 10.1007/s10822-019-00188-x.
Peptide-Protein Binding Investigated by Far-IR Spectroscopy and Molecular Dynamics Simulations
COTE, Yoann, NOMINÉ, Yves, RAMIREZ, J., HELLWIG, Petra et STOTE, Roland H., 2017. Peptide-Protein Binding Investigated by Far-IR Spectroscopy and Molecular Dynamics Simulations. Biophys J [en ligne]. 2017. Vol. 112, n° 12pp. 2575-2588. [Consultésans date]. DOI 10.1016/j.bpj.2017.05.018. Consulté de : http://www.ncbi.nlm.nih.gov/pubmed/286369141. PMC5479146.

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