Laboratoire d'Innovation Thérapeutique - LIT - UMR7200

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Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16INK4A re-expression related to UHRF1 and DNMT1 down-regulation
Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation
Methylation of imidazoline related compounds leads to loss of alpha(2)-adrenoceptor affinity. Synthesis and biological evaluation of selective I(1) imidazoline receptor ligands
Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6
Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications
New fluorescein precursors for live bacteria detection
Novel amino-pyrroline derivatives, and use thereof in the prevention and/or treatment of metabolic syndrome
On the use of capillary cytometry for assessing the bactericidal effect of TiO2. Identification and involvement of reactive oxygen species
Oxidative Stress Type Influences the Properties of Antioxidants Containing Polyphenols in RINm5F Beta Cells
pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery
Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo
Prokineticin 1 receptor agonists and their uses
Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo
Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines
Quantitative structure-property relationship modeling: a valuable support in high-throughput screening quality control
Rapid and scalable synthesis of innovative unnatural α,β or γ-amino acids functionalized with tertiary amines on their side-chains.
Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells
Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging
A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis

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