Laboratoire d'Innovation Thérapeutique - LIT - UMR7200

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Cyclocarbopalladation as a Key Step in Cascade Reactions : recent developments
Cyclohydrocarbonylation-Based Strategy toward Poly- Substituted Piperidines
Deciphering of the mechanism of the anti-asthmatic action of the CXCL12 neutraligand, chalcone 4
Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model
Design of a Liposomal Candidate Vaccine Against Pseudomonas aeruginosa and its Evaluation in Triggering Systemic and Lung Mucosal Immunity
Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors
Desymmetrizing Hydroformylation of Dihydromuconic Acid Diesters: Application to the Synthesis of (±)-Vindeburnol
Development of Dipeptidic hGPR54 Agonists.
Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine
Diastereoselective Synthesis of Novel Aza-diketopiperazines via a Domino Cyclohydrocarbonylation/Addition Process
Discovery and characterization of an endogenous CXCR4 antagonist
Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors
Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1
Evolution of coumaroyl conjugate 3‐hydroxylases in land plants: Lignin biosynthesis and defense
Evolutionarily conserved SFPH proteins as therapeutic targets for a myriad of diseases
An Expeditious and Atom-Economical Synthesis of a New Generation of Substituted [4.6.4.6]Fenestradienes
Expeditious cascade reactions: controlled syntheses of fenestradienes and cyclooctatrienes under palladium catalysis

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