Laboratoire d'Innovation Thérapeutique - LIT - UMR7200

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Synthesis of Benzo[c]silole Derivatives Bearing a Tetrasubstituted Exocyclic C=C Double Bond by Palladium-Catalyzed Domino Reactions
Synthesis of Cyclooctatetraenes through a Palladium-Catalyzed Cascade Reaction
Synthesis of exotic polycycles such as cyclooctatrienes and fenestrenes with differential pro-apoptotic activities on human TRAIL-resistant metastatic cell lines
Synthesis of original polycycles containing five-, six- and seven-membered rings through cyclocarbopalladations/C–H activation cascade reactions
Synthesis of Polyheterocyclic Tropones by [2 + 2 + 2 + 1] Carbonylative Cycloaddition of Triynes
Synthesis of Sulfur-Containing Exo -Bicyclic Dienes and Their Diels–Alder Reactions To Access Thiacycle-Fused Polycyclic Systems
Synthesis of sulfur heterocycles via domino metal-mediated reactions
The synthetic flavagline FL3 spares normal human skin cells from its cytotoxic effect via an activation of Bad
Tandem Double-Cross-Coupling/Hydrothiolation Reaction of 2-Sulfenyl Benzimidazoles with Boronic Acids
Tandem β-Alkylation−α-Arylation of Amines by Carbolithiation and Rearrangement of N-Carbamoyl Enamines (Vinyl Ureas)
Three-step isolation of a new pregnane from Cynanchum marnieranum Rauh (Apocynaceae)
Un neutraligand de la chimiokine CXCL12 inhibe la fibroprolifération dans un modèle de bronchiolite oblitérante après transplantation hétérotopique de trachée chez la souris
Versatile Synthetic Approach for Selective Diversification of Bicyclic Aza-Diketopiperazines
WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

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