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Differential gene expression--how to find new analgesic targets.
Differential gene expression--how to find new analgesic targets.
Pas de texte intégral
Befort K, Costigan M, Woolf C J
Current opinion in investigational drugs (London, England : 2000)
[35S]GTP gamma S binding: a tool to evaluate functional activity of a cloned opioid receptor transiently expressed in COS cells.
[35S]GTP gamma S binding: a tool to evaluate functional activity of a cloned opioid receptor transiently expressed in COS cells.
Pas de texte intégral
Befort K, Tabbara L, Kieffer B L
Neurochemical research
Chromosomal localization of the delta opioid receptor gene to human 1p34.3-p36.1 and mouse 4D bands by in situ hybridization.
Chromosomal localization of the delta opioid receptor gene to human 1p34.3-p36.1 and mouse 4D bands by in situ hybridization.
Pas de texte intégral
Befort K, Mattéi M G, Roeckel N, Kieffer B
Genomics
Constitutive activation of the delta opioid receptor by mutations in transmembrane domains III and VII.
Constitutive activation of the delta opioid receptor by mutations in transmembrane domains III and VII.
Pas de texte intégral
Befort K, Zilliox C, Filliol D, Yue S, Kieffer B L
The Journal of biological chemistry
Role of aromatic transmembrane residues of the delta-opioid receptor in ligand recognition.
Role of aromatic transmembrane residues of the delta-opioid receptor in ligand recognition.
Pas de texte intégral
Befort K, Tabbara L, Kling D, Maigret B, Kieffer B L
The Journal of biological chemistry
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
Pas de texte intégral
Kieffer B L, Befort K, Gaveriaux-Ruff C, Hirth C G
Proceedings of the National Academy of Sciences of the United States of America
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study
Pas de texte intégral
Fonteneau M., Filliol D., Anglard P., Befort K., Romieu P., Zwiller J.
2016-11-23
Genes, Brain and Behavior
Laboratoire de Neurosciences Cognitives et Adaptatives
UMR 7364, CNRS, Université de Strasbourg
Strasbourg France
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains
Pas de texte intégral
Ayranci G., Befort K., Lalanne L., Kieffer B. L., Lutz P.-E.
2015-06
Psychopharmacology
Delta-opioid receptor gene expression in the mouse forebrain: localization in cholinergic neurons of the striatum.
Delta-opioid receptor gene expression in the mouse forebrain: localization in cholinergic neurons of the striatum.
Pas de texte intégral
Le Moine C, Kieffer B, Gaveriaux-Ruff C, Befort K, Bloch B
Neuroscience
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study
Pas de texte intégral
Fonteneau M., Filliol D., Anglard P., Befort K., Romieu P., Zwiller J.
2016-11-23
Genes, Brain and Behavior
Laboratoire de Neurosciences Cognitives et Adaptatives
UMR 7364, CNRS, Université de Strasbourg
Strasbourg France
Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors.
Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors.
Pas de texte intégral
Gavériaux-Ruff C, Peluso J, Befort K, Simonin F, Zilliox C, Kieffer B L
Brain research. Molecular brain research
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.
Pas de texte intégral
Ayranci G, Befort K, Lalanne L, Kieffer B L, Lutz P-E
Psychopharmacology
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.
Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.
Pas de texte intégral
Ayranci G, Befort K, Lalanne L, Kieffer B L, Lutz P-E
Psychopharmacology
Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence
Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence
Pas de texte intégral
Lalanne L., Ayranci G., Filliol D., Gavériaux-Ruff C., Befort K., Kieffer B. L., Lutz P-E
2016-03-22
Addiction Biology
Translational Medicine and Neurogenetics Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U 964, CNRS UMR 7104
Université de Strasbourg
France
The conserved aspartate residue in the third putative transmembrane domain of the delta-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site.
The conserved aspartate residue in the third putative transmembrane domain of the delta-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site.
Pas de texte intégral
Befort K, Tabbara L, Bausch S, Chavkin C, Evans C, Kieffer B, P50 DA005010
Molecular pharmacology
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.
Pas de texte intégral
Befort K, Filliol D, Decaillot F M, Gaveriaux-Ruff C, Hoehe M R, Kieffer B L
The Journal of biological chemistry
The human delta-opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in human brain.
The human delta-opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in human brain.
Pas de texte intégral
Simonin F, Befort K, Gavériaux-Ruff C, Matthes H, Nappey V, Lannes B, Micheletti G, Kieffer B
Molecular pharmacology
Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence.
Kappa opioid receptor antagonism and chronic antidepressant treatment have beneficial activities on social interactions and grooming deficits during heroin abstinence.
Pas de texte intégral
Lalanne L, Ayranci G, Filliol D, Gavériaux-Ruff C, Befort K, Kieffer B L, Lutz P-E, P50 DA005010
Addiction biology
RSK2 signaling in brain habenula contributes to place aversion learning
RSK2 signaling in brain habenula contributes to place aversion learning
Pas de texte intégral
Darcq E., Koebel P., Del Boca C., Pannetier S., Kirstetter A.-S., Garnier J.-M., Hanauer A., Befort K., Kieffer B. L.
2011-08-18
Transcriptome analysis identifies genes with enriched expression in the mouse central extended amygdala
Transcriptome analysis identifies genes with enriched expression in the mouse central extended amygdala
Pas de texte intégral
Becker J.A.J., Befort K., Blad C., Filliol D., Ghate A., Dembele D., Thibault C., Koch M., Muller J., Lardenois A., Poch O., Kieffer B.L.
2008-10
Neuroscience

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