Résultats de la recherche

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Le RF9, un antagoniste puissant et sélectif des récepteurs du neuropeptide FF, prévient le développement de la tolérance aux opiacés
Neuropeptide FF and neuropeptide VF inhibit GABAergic neurotransmission in parvocellular neurons of the rat hypothalamic paraventricular nucleus
Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor
Cyclic nucleotide phosphodiesterase type 4 inhibitors
A novel, conformation‐specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia
Design, synthesis and structure-activity relationships of a series of 9-substituted adenine derivatives as selective phosphodiesterase type-4 inhibitors
Development of a Peptidomimetic Antagonist of Neuropeptide FF Receptors for the Prevention of Opioid-Induced Hyperalgesia
Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103
Allosteric Functional Switch of Neurokinin A-Mediated Signaling at the Neurokinin NK2 Receptor: Structural Exploration
RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia
Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors
Trisubstitution of pyridine through sequential and regioselective palladium cross-coupling reactions affording analogs of known GPR54 antagonists
Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors
Ornithine- and lysine-derivatives for the treatment of pain
Neuropeptide FF and prolactin-releasing peptide decrease cortical excitability through activation of NPFF receptors.
Development of Dipeptidic hGPR54 Agonists.
Development of a L-Tryptophan-Based Ligand for Regioselective Copper Catalyzed N 2 -Arylation of 1,2,3-Triazoles
D-Glucose: An Efficient Reducing Agent for a Copper(II)-Mediated Arylation of Primary Amines in Water
Efficient and mild Ullmann-type N-arylation of amides, carbamates, and azoles in water.

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