Résultats de la recherche

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Structural characterization of metal binding to a cold-adapted frataxin
Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family
X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition
Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase
Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury
Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10
Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10
Crystal packing modifies ligand binding affinity: the case of aldose reductase
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors
New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
Modulation of aldose reductase inhibition by halogen bond tuning
Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design
Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders
Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface
Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography
Synthesis of quaternary alpha-amino acid-based arginase inhibitors via the Ugi reaction
Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger
Iminosugar‐Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

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