Résultats de la recherche

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Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome
Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome
The in vivo Down syndrome genomic library in mouse
Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models
The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model
DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels
Specific targeting of the GABA-A receptor alpha5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice
Deletion of the App-Runx1 region in mice models human partial monosomy 21
Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics