Résultats de la recherche

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Why and how to find neutraligands targeting chemokines?
Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor
A Rapid and Versatile Method to Label Receptor Ligands Using “Click” Chemistry:  Validation with the Muscarinic M1 Antagonist Pirenzepine
Quantitative structure-property relationship modeling: a valuable support in high-throughput screening quality control
A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain
A novel, conformation‐specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications
Fluorescent Derivatives of AC-42 To Probe Bitopic Orthosteric/Allosteric Binding Mechanisms on Muscarinic M1 Receptors
Diastereoselective Synthesis of Novel Aza-diketopiperazines via a Domino Cyclohydrocarbonylation/Addition Process
An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice
A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis
Versatile Synthetic Approach for Selective Diversification of Bicyclic Aza-Diketopiperazines
Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells
Allosteric Functional Switch of Neurokinin A-Mediated Signaling at the Neurokinin NK2 Receptor: Structural Exploration
Fluorogenic squaraine dimers with polarity-sensitive folding as bright far-red probes for background-free bioimaging
Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging
Les neutraligands à l'assaut des chimiokines
Identification of CCL17 neutraligands targeting atopic diseases
Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo
Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines

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