Résultats de la recherche

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Why and how to find neutraligands targeting chemokines?
Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor
A Rapid and Versatile Method to Label Receptor Ligands Using “Click” Chemistry:  Validation with the Muscarinic M1 Antagonist Pirenzepine
Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications
A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain
Quantitative structure-property relationship modeling: a valuable support in high-throughput screening quality control
Fluorescent Derivatives of AC-42 To Probe Bitopic Orthosteric/Allosteric Binding Mechanisms on Muscarinic M1 Receptors
A novel, conformation‐specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
Diastereoselective Synthesis of Novel Aza-diketopiperazines via a Domino Cyclohydrocarbonylation/Addition Process
Fluorogenic squaraine dimers with polarity-sensitive folding as bright far-red probes for background-free bioimaging
Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging
Les neutraligands à l'assaut des chimiokines
Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo
Un neutraligand de la chimiokine CXCL12 inhibe la fibroprolifération dans un modèle de bronchiolite oblitérante après transplantation hétérotopique de trachée chez la souris
Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines
Identification of CCL17 neutraligands targeting atopic diseases
A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis
Versatile Synthetic Approach for Selective Diversification of Bicyclic Aza-Diketopiperazines
Allosteric Functional Switch of Neurokinin A-Mediated Signaling at the Neurokinin NK2 Receptor: Structural Exploration
An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice

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