Résultats de la recherche

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X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition
Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase
Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury
Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10
Crystal packing modifies ligand binding affinity: the case of aldose reductase
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors
Modulation of aldose reductase inhibition by halogen bond tuning
Synthesis of quaternary alpha-amino acid-based arginase inhibitors via the Ugi reaction

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